Gene-specific Copy Number Variation Probe-ZP3
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| Catalog: |
CNVFP-ZP3-23958 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ZP3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ZP3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ZP3 genes. This product achieves the purpose of detection by hybridizing with the ZP3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Zona Pellucida Glycoprotein 3 |
| Gene Summary [Provided by RefSeq] |
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
ZP3 |
| Location |
7q11.23 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 76026840-76071388 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ZP3-23958-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ZP3-23958-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ZP3-23958-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ZP3-23958-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ZP3-23958-AQ |
467nm |
418nm |
|
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