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Gene-specific Copy Number Variation Probe-TP53

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Catalog: CNVFP-TP53-24031
Classification: Copy Number Variation
Description: Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TP53). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application: TP53 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TP53 genes. This product achieves the purpose of detection by hybridizing with the TP53 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Category: Copy Number Variation
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name tumor protein p53
Gene Summary [Provided by RefSeq] This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Gene Symbol TP53
Location 17p13.1
Chromosome Chromosome17
Coordinates This gene maps to 7571719-7590863 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR CNVFP-TP53-24031-OR 573nm 548nm
2 RE CNVFP-TP53-24031-RE 599nm 580nm
3 GO CNVFP-TP53-24031-GO 551nm 525nm
4 GR CNVFP-TP53-24031-GR 515nm 491nm
5 AQ CNVFP-TP53-24031-AQ 467nm 418nm

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