Gene-specific Copy Number Variation Probe-CCNE1
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| Catalog: |
CNVFP-CCNE1-24027 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CCNE1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CCNE1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CCNE1 genes. This product achieves the purpose of detection by hybridizing with the CCNE1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
cyclin E1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. [provided by RefSeq, Apr 2016] |
| Gene Symbol |
CCNE1 |
| Location |
19q12 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 30302900-30315215 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CCNE1-24027-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CCNE1-24027-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CCNE1-24027-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CCNE1-24027-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CCNE1-24027-AQ |
467nm |
418nm |
|
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