Gene-specific Copy Number Variation Probe-WRN
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Catalog: |
CNVFP-WRN-22967 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (WRN). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
WRN Gene-specific copy number variation probes are mainly used to detect the copy number variation related to WRN genes. This product achieves the purpose of detection by hybridizing with the WRN gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Werner Syndrome RecQ Like Helicase |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017] |
Gene Symbol |
WRN |
Location |
8p12 |
Chromosome |
Chromosome8 |
Coordinates |
This gene maps to 30890777-31031277 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-WRN-22967-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-WRN-22967-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-WRN-22967-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-WRN-22967-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-WRN-22967-AQ |
467nm |
418nm |
|
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