Gene-specific Copy Number Variation Probe-WAS
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| Catalog: |
CNVFP-WAS-23153 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (WAS). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
WAS Gene-specific copy number variation probes are mainly used to detect the copy number variation related to WAS genes. This product achieves the purpose of detection by hybridizing with the WAS gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Wiskott-Aldrich Syndrome |
| Gene Summary [Provided by RefSeq] |
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
WAS |
| Location |
Xp11.23 |
| Chromosome |
ChromosomeX |
| Coordinates |
This gene maps to 48542185-48549817 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-WAS-23153-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-WAS-23153-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-WAS-23153-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-WAS-23153-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-WAS-23153-AQ |
467nm |
418nm |
|
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