Gene-specific Copy Number Variation Probe-VKORC1
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Catalog: |
CNVFP-VKORC1-22840 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (VKORC1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
VKORC1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to VKORC1 genes. This product achieves the purpose of detection by hybridizing with the VKORC1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Vitamin K Epoxide Reductase Complex Subunit 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
Gene Symbol |
VKORC1 |
Location |
16p11.2 |
Chromosome |
Chromosome16 |
Coordinates |
This gene maps to 31102174-31106276 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-VKORC1-22840-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-VKORC1-22840-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-VKORC1-22840-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-VKORC1-22840-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-VKORC1-22840-AQ |
467nm |
418nm |
|
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