Gene-specific Copy Number Variation Probe-VAV1
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Catalog: |
CNVFP-VAV1-22862 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (VAV1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
VAV1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to VAV1 genes. This product achieves the purpose of detection by hybridizing with the VAV1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Vav Guanine Nucleotide Exchange Factor 1 |
Gene Summary [Provided by RefSeq] |
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012] |
Gene Symbol |
VAV1 |
Location |
19p13.3 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 6772721-6857371 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-VAV1-22862-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-VAV1-22862-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-VAV1-22862-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-VAV1-22862-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-VAV1-22862-AQ |
467nm |
418nm |
|
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