Gene-specific Copy Number Variation Probe-UPF3B
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| Catalog: |
CNVFP-UPF3B-22736 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (UPF3B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
UPF3B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to UPF3B genes. This product achieves the purpose of detection by hybridizing with the UPF3B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
UPF3B, Regulator Of Nonsense Mediated MRNA Decay |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
UPF3B |
| Location |
Xq24 |
| Chromosome |
ChromosomeX |
| Coordinates |
This gene maps to 118967988-118986991 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-UPF3B-22736-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-UPF3B-22736-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-UPF3B-22736-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-UPF3B-22736-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-UPF3B-22736-AQ |
467nm |
418nm |
|
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