Gene-specific Copy Number Variation Probe-UNC45B
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Catalog: |
CNVFP-UNC45B-22771 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (UNC45B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
UNC45B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to UNC45B genes. This product achieves the purpose of detection by hybridizing with the UNC45B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Unc-45 Myosin Chaperone B |
Gene Summary [Provided by RefSeq] |
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
Gene Symbol |
UNC45B |
Location |
17q12 |
Chromosome |
Chromosome17 |
Coordinates |
This gene maps to 33474835-33516364 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-UNC45B-22771-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-UNC45B-22771-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-UNC45B-22771-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-UNC45B-22771-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-UNC45B-22771-AQ |
467nm |
418nm |
|
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