Gene-specific Copy Number Variation Probe-UCP3
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| Catalog: |
CNVFP-UCP3-22489 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (UCP3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
UCP3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to UCP3 genes. This product achieves the purpose of detection by hybridizing with the UCP3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Uncoupling Protein 3 |
| Gene Summary [Provided by RefSeq] |
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008] |
| Gene Symbol |
UCP3 |
| Location |
11q13.4 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 73711325-73720282 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-UCP3-22489-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-UCP3-22489-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-UCP3-22489-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-UCP3-22489-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-UCP3-22489-AQ |
467nm |
418nm |
|
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