Gene-specific Copy Number Variation Probe-UBE3B
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| Catalog: |
CNVFP-UBE3B-22540 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (UBE3B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
UBE3B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to UBE3B genes. This product achieves the purpose of detection by hybridizing with the UBE3B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Ubiquitin Protein Ligase E3B |
| Gene Summary [Provided by RefSeq] |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012] |
| Gene Symbol |
UBE3B |
| Location |
12q24.11 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 109915438-109974507 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-UBE3B-22540-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-UBE3B-22540-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-UBE3B-22540-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-UBE3B-22540-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-UBE3B-22540-AQ |
467nm |
418nm |
|
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