Gene-specific Copy Number Variation Probe-TYROBP
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Catalog: |
CNVFP-TYROBP-22608 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TYROBP). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
TYROBP Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TYROBP genes. This product achieves the purpose of detection by hybridizing with the TYROBP gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
TYRO Protein Tyrosine Kinase Binding Protein |
Gene Summary [Provided by RefSeq] |
This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010] |
Gene Symbol |
TYROBP |
Location |
19q13.12 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 36395302-36399211 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-TYROBP-22608-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-TYROBP-22608-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-TYROBP-22608-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-TYROBP-22608-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-TYROBP-22608-AQ |
467nm |
418nm |
|
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