Gene-specific Copy Number Variation Probe-TYMS
Add to Cart
| Catalog: |
CNVFP-TYMS-22613 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TYMS). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TYMS Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TYMS genes. This product achieves the purpose of detection by hybridizing with the TYMS gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Thymidylate Synthetase |
| Gene Summary [Provided by RefSeq] |
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017] |
| Gene Symbol |
TYMS |
| Location |
18p11.32 |
| Chromosome |
Chromosome18 |
| Coordinates |
This gene maps to 657603-673499 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TYMS-22613-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TYMS-22613-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TYMS-22613-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TYMS-22613-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TYMS-22613-AQ |
467nm |
418nm |
|
Other Products
