Gene-specific Copy Number Variation Probe-TXNRD3
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| Catalog: |
CNVFP-TXNRD3-22616 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TXNRD3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TXNRD3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TXNRD3 genes. This product achieves the purpose of detection by hybridizing with the TXNRD3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Thioredoxin Reductase 3 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes the third TrxR, which unlike the other two isozymes, contains an additional N-terminal glutaredoxin (Grx) domain, and shows highest expression in testis. The Grx domain allows this isozyme to participate in both Trx and glutathione systems. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. Experimental evidence suggests the use of a non-AUG (CUG) codon as a translation initiation codon (PMID:20018845). [provided by RefSeq, Aug 2017] |
| Gene Symbol |
TXNRD3 |
| Location |
3q21.3 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 126325894-126373967 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TXNRD3-22616-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TXNRD3-22616-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TXNRD3-22616-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TXNRD3-22616-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TXNRD3-22616-AQ |
467nm |
418nm |
|
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