Gene-specific Copy Number Variation Probe-TXNRD2
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| Catalog: |
CNVFP-TXNRD2-22617 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TXNRD2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TXNRD2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TXNRD2 genes. This product achieves the purpose of detection by hybridizing with the TXNRD2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Thioredoxin Reductase 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene. [provided by RefSeq, Jun 2017] |
| Gene Symbol |
TXNRD2 |
| Location |
22q11.21 |
| Chromosome |
Chromosome22 |
| Coordinates |
This gene maps to 19863039-19929359 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TXNRD2-22617-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TXNRD2-22617-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TXNRD2-22617-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TXNRD2-22617-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TXNRD2-22617-AQ |
467nm |
418nm |
|
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