Gene-specific Copy Number Variation Probe-TWIST1
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Catalog: |
CNVFP-TWIST1-22640 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TWIST1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
TWIST1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TWIST1 genes. This product achieves the purpose of detection by hybridizing with the TWIST1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Twist Family BHLH Transcription Factor 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017] |
Gene Symbol |
TWIST1 |
Location |
7p21.1 |
Chromosome |
Chromosome7 |
Coordinates |
This gene maps to 19155090-19157295 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-TWIST1-22640-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-TWIST1-22640-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-TWIST1-22640-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-TWIST1-22640-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-TWIST1-22640-AQ |
467nm |
418nm |
|
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