Gene-specific Copy Number Variation Probe-TUBA1A
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| Catalog: |
CNVFP-TUBA1A-22342 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TUBA1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TUBA1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TUBA1A genes. This product achieves the purpose of detection by hybridizing with the TUBA1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Tubulin Alpha 1a |
| Gene Summary [Provided by RefSeq] |
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] |
| Gene Symbol |
TUBA1A |
| Location |
12q13.12 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 49578582-49582861 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TUBA1A-22342-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TUBA1A-22342-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TUBA1A-22342-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TUBA1A-22342-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TUBA1A-22342-AQ |
467nm |
418nm |
|
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