Gene-specific Copy Number Variation Probe-TRAV23DV6
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| Catalog: |
CNVFP-TRAV23DV6-21690 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TRAV23DV6). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TRAV23DV6 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TRAV23DV6 genes. This product achieves the purpose of detection by hybridizing with the TRAV23DV6 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
T Cell Receptor Alpha Variable 23/delta Variable 6 |
| Gene Summary [Provided by RefSeq] |
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] |
| Gene Symbol |
TRAV23DV6 |
| Location |
14q11.2 |
| Chromosome |
Chromosome14 |
| Coordinates |
This gene maps to 22086451-22086960 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TRAV23DV6-21690-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TRAV23DV6-21690-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TRAV23DV6-21690-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TRAV23DV6-21690-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TRAV23DV6-21690-AQ |
467nm |
418nm |
|
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