Gene-specific Copy Number Variation Probe-TPSAB1
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| Catalog: |
CNVFP-TPSAB1-21383 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TPSAB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TPSAB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TPSAB1 genes. This product achieves the purpose of detection by hybridizing with the TPSAB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Tryptase Alpha/beta 1 |
| Gene Summary [Provided by RefSeq] |
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
TPSAB1 |
| Location |
16p13.3 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 1290677-1292555 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TPSAB1-21383-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TPSAB1-21383-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TPSAB1-21383-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TPSAB1-21383-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TPSAB1-21383-AQ |
467nm |
418nm |
|
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