Gene-specific Copy Number Variation Probe-TPO
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Catalog: |
CNVFP-TPO-21469 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TPO). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
TPO Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TPO genes. This product achieves the purpose of detection by hybridizing with the TPO gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Thyroid Peroxidase |
Gene Summary [Provided by RefSeq] |
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] |
Gene Symbol |
TPO |
Location |
2p25.3 |
Chromosome |
Chromosome2 |
Coordinates |
This gene maps to 1417232-1546499 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-TPO-21469-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-TPO-21469-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-TPO-21469-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-TPO-21469-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-TPO-21469-AQ |
467nm |
418nm |
|
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