Gene-specific Copy Number Variation Probe-TPMT
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| Catalog: |
CNVFP-TPMT-21471 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TPMT). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TPMT Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TPMT genes. This product achieves the purpose of detection by hybridizing with the TPMT gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Thiopurine S-methyltransferase |
| Gene Summary [Provided by RefSeq] |
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014] |
| Gene Symbol |
TPMT |
| Location |
6p22.3 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 18128544-18155374 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TPMT-21471-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TPMT-21471-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TPMT-21471-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TPMT-21471-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TPMT-21471-AQ |
467nm |
418nm |
|
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