Gene-specific Copy Number Variation Probe-TOP3B
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Catalog: |
CNVFP-TOP3B-21144 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TOP3B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
TOP3B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TOP3B genes. This product achieves the purpose of detection by hybridizing with the TOP3B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
DNA Topoisomerase III Beta |
Gene Summary [Provided by RefSeq] |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013] |
Gene Symbol |
TOP3B |
Location |
22q11.22 |
Chromosome |
Chromosome22 |
Coordinates |
This gene maps to 22311402-22337147 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-TOP3B-21144-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-TOP3B-21144-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-TOP3B-21144-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-TOP3B-21144-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-TOP3B-21144-AQ |
467nm |
418nm |
|
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