Gene-specific Copy Number Variation Probe-TNFSF11
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| Catalog: |
CNVFP-TNFSF11-21209 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TNFSF11). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TNFSF11 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TNFSF11 genes. This product achieves the purpose of detection by hybridizing with the TNFSF11 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
TNF Superfamily Member 11 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
TNFSF11 |
| Location |
13q14.11 |
| Chromosome |
Chromosome13 |
| Coordinates |
This gene maps to 43136871-43182149 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TNFSF11-21209-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TNFSF11-21209-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TNFSF11-21209-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TNFSF11-21209-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TNFSF11-21209-AQ |
467nm |
418nm |
|
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