Gene-specific Copy Number Variation Probe-TGFB1
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| Catalog: |
CNVFP-TGFB1-20547 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TGFB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TGFB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TGFB1 genes. This product achieves the purpose of detection by hybridizing with the TGFB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Transforming Growth Factor Beta 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016] |
| Gene Symbol |
TGFB1 |
| Location |
19q13.2 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 41836811-41859831 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TGFB1-20547-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TGFB1-20547-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TGFB1-20547-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TGFB1-20547-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TGFB1-20547-AQ |
467nm |
418nm |
|
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