Gene-specific Copy Number Variation Probe-TDG
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| Catalog: |
CNVFP-TDG-20707 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (TDG). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
TDG Gene-specific copy number variation probes are mainly used to detect the copy number variation related to TDG genes. This product achieves the purpose of detection by hybridizing with the TDG gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Thymine DNA Glycosylase |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
TDG |
| Location |
12q23.3 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 104359592-104382656 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-TDG-20707-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-TDG-20707-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-TDG-20707-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-TDG-20707-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-TDG-20707-AQ |
467nm |
418nm |
|
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