Gene-specific Copy Number Variation Probe-STIL
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Catalog: |
CNVFP-STIL-20144 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (STIL). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
STIL Gene-specific copy number variation probes are mainly used to detect the copy number variation related to STIL genes. This product achieves the purpose of detection by hybridizing with the STIL gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
STIL, Centriolar Assembly Protein |
Gene Summary [Provided by RefSeq] |
This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Gene Symbol |
STIL |
Location |
1p33 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 47715810-47779819 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-STIL-20144-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-STIL-20144-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-STIL-20144-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-STIL-20144-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-STIL-20144-AQ |
467nm |
418nm |
|
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