Gene-specific Copy Number Variation Probe-STAT5A
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Catalog: |
CNVFP-STAT5A-20157 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (STAT5A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
STAT5A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to STAT5A genes. This product achieves the purpose of detection by hybridizing with the STAT5A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Signal Transducer And Activator Of Transcription 5A |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] |
Gene Symbol |
STAT5A |
Location |
17q21.2 |
Chromosome |
Chromosome17 |
Coordinates |
This gene maps to 40439564-40463960 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-STAT5A-20157-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-STAT5A-20157-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-STAT5A-20157-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-STAT5A-20157-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-STAT5A-20157-AQ |
467nm |
418nm |
|
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