Gene-specific Copy Number Variation Probe-STAT3
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| Catalog: |
CNVFP-STAT3-20159 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (STAT3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
STAT3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to STAT3 genes. This product achieves the purpose of detection by hybridizing with the STAT3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Signal Transducer And Activator Of Transcription 3 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
STAT3 |
| Location |
17q21.2 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 40465342-40540513 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-STAT3-20159-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-STAT3-20159-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-STAT3-20159-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-STAT3-20159-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-STAT3-20159-AQ |
467nm |
418nm |
|
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