Gene-specific Copy Number Variation Probe-SREBF1
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| Catalog: |
CNVFP-SREBF1-19937 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SREBF1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
SREBF1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SREBF1 genes. This product achieves the purpose of detection by hybridizing with the SREBF1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Sterol Regulatory Element Binding Transcription Factor 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017] |
| Gene Symbol |
SREBF1 |
| Location |
17p11.2 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 17714662-17740325 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-SREBF1-19937-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-SREBF1-19937-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-SREBF1-19937-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-SREBF1-19937-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-SREBF1-19937-AQ |
467nm |
418nm |
|
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