Gene-specific Copy Number Variation Probe-SPHK1
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Catalog: |
CNVFP-SPHK1-19627 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SPHK1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
SPHK1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SPHK1 genes. This product achieves the purpose of detection by hybridizing with the SPHK1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Sphingosine Kinase 1 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Phosphorylation of this protein alters its catalytic activity and promotes its translocation to the plasma membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017] |
Gene Symbol |
SPHK1 |
Location |
17q25.1 |
Chromosome |
Chromosome17 |
Coordinates |
This gene maps to 74380689-74383941 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-SPHK1-19627-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-SPHK1-19627-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-SPHK1-19627-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-SPHK1-19627-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-SPHK1-19627-AQ |
467nm |
418nm |
|
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