Gene-specific Copy Number Variation Probe-SORD
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Catalog: |
CNVFP-SORD-19604 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SORD). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
SORD Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SORD genes. This product achieves the purpose of detection by hybridizing with the SORD gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Sorbitol Dehydrogenase |
Gene Summary [Provided by RefSeq] |
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010] |
Gene Symbol |
SORD |
Location |
15q21.1 |
Chromosome |
Chromosome15 |
Coordinates |
This gene maps to 45315301-45367287 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-SORD-19604-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-SORD-19604-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-SORD-19604-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-SORD-19604-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-SORD-19604-AQ |
467nm |
418nm |
|
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