Gene-specific Copy Number Variation Probe-SMAD1
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Catalog: |
CNVFP-SMAD1-19016 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SMAD1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
SMAD1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SMAD1 genes. This product achieves the purpose of detection by hybridizing with the SMAD1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
SMAD Family Member 1 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
Gene Symbol |
SMAD1 |
Location |
4q31.21 |
Chromosome |
Chromosome4 |
Coordinates |
This gene maps to 146402950-146480325 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-SMAD1-19016-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-SMAD1-19016-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-SMAD1-19016-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-SMAD1-19016-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-SMAD1-19016-AQ |
467nm |
418nm |
|
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