Gene-specific Copy Number Variation Probe-SIRPA
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| Catalog: |
CNVFP-SIRPA-18379 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SIRPA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
SIRPA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SIRPA genes. This product achieves the purpose of detection by hybridizing with the SIRPA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Signal Regulatory Protein Alpha |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
SIRPA |
| Location |
20p13 |
| Chromosome |
Chromosome20 |
| Coordinates |
This gene maps to 1874812-1920540 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-SIRPA-18379-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-SIRPA-18379-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-SIRPA-18379-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-SIRPA-18379-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-SIRPA-18379-AQ |
467nm |
418nm |
|
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