Gene-specific Copy Number Variation Probe-SH2D1A
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| Catalog: |
CNVFP-SH2D1A-18478 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SH2D1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
SH2D1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SH2D1A genes. This product achieves the purpose of detection by hybridizing with the SH2D1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
SH2 Domain Containing 1A |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
SH2D1A |
| Location |
Xq25 |
| Chromosome |
ChromosomeX |
| Coordinates |
This gene maps to 123480131-123507010 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-SH2D1A-18478-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-SH2D1A-18478-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-SH2D1A-18478-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-SH2D1A-18478-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-SH2D1A-18478-AQ |
467nm |
418nm |
|
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