Gene-specific Copy Number Variation Probe-SFTPB
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Catalog: |
CNVFP-SFTPB-18477 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SFTPB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
SFTPB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SFTPB genes. This product achieves the purpose of detection by hybridizing with the SFTPB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Surfactant Protein B |
Gene Summary [Provided by RefSeq] |
This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010] |
Gene Symbol |
SFTPB |
Location |
2p11.2 |
Chromosome |
Chromosome2 |
Coordinates |
This gene maps to 85884439-85895864 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-SFTPB-18477-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-SFTPB-18477-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-SFTPB-18477-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-SFTPB-18477-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-SFTPB-18477-AQ |
467nm |
418nm |
|
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