Gene-specific Copy Number Variation Probe-SCUBE3
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| Catalog: |
CNVFP-SCUBE3-18071 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (SCUBE3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
SCUBE3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to SCUBE3 genes. This product achieves the purpose of detection by hybridizing with the SCUBE3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Signal Peptide, CUB Domain And EGF Like Domain Containing 3 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the signal peptide, complement subcomponents C1r/C1s, Uegf, bone morphogenetic protein-1 and epidermal growth factor-like domain containing protein family. Overexpression of this gene in human embryonic kidney cells results in secretion of a glycosylated form of the protein that forms oligomers and tethers to the cell surface. This gene is upregulated in lung cancer tumor tissue compared to healthy tissue and is associated with loss of the epithelial marker E-cadherin and with increased expression of vimentin, a mesenchymal marker. In addition, the protein encoded by this gene is a transforming growth factor beta receptor ligand, and when secreted by cancer cells, it can be cleaved in vitro to release the N-terminal epidermal growth factor-like repeat domain and the C-terminal complement subcomponents C1r/C1s domain. Both the full length protein and C-terminal fragment can bind to the transforming growth factor beta type II receptor to promote the epithelial-mesenchymal transition and tumor angiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Gene Symbol |
SCUBE3 |
| Location |
6p21.31 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 35182189-35218609 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-SCUBE3-18071-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-SCUBE3-18071-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-SCUBE3-18071-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-SCUBE3-18071-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-SCUBE3-18071-AQ |
467nm |
418nm |
|
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