Gene-specific Copy Number Variation Probe-RUNX2
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Catalog: |
CNVFP-RUNX2-17689 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RUNX2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
RUNX2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RUNX2 genes. This product achieves the purpose of detection by hybridizing with the RUNX2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Runt Related Transcription Factor 2 |
Gene Summary [Provided by RefSeq] |
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016] |
Gene Symbol |
RUNX2 |
Location |
6p21.1 |
Chromosome |
Chromosome6 |
Coordinates |
This gene maps to 45296053-45518819 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-RUNX2-17689-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-RUNX2-17689-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-RUNX2-17689-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-RUNX2-17689-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-RUNX2-17689-AQ |
467nm |
418nm |
|
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