Gene-specific Copy Number Variation Probe-RPE65
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| Catalog: |
CNVFP-RPE65-17539 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RPE65). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
RPE65 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RPE65 genes. This product achieves the purpose of detection by hybridizing with the RPE65 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
RPE65, Retinoid Isomerohydrolase |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a component of the vitamin A visual cycle of the retina which supplies the 11-cis retinal chromophore of the photoreceptors opsin visual pigments. It is a member of the carotenoid cleavage oxygenase superfamily. All members of this superfamily are non-heme iron oxygenases with a seven-bladed propeller fold and oxidatively cleave carotenoid carbon:carbon double bonds. However, the protein encoded by this gene has acquired a divergent function that involves the concerted O-alkyl ester cleavage of its all-trans retinyl ester substrate and all-trans to 11-cis double bond isomerization of the retinyl moiety. As such, it performs the essential enzymatic isomerization step in the synthesis of 11-cis retinal. Mutations in this gene are associated with early-onset severe blinding disorders such as Leber congenital. [provided by RefSeq, Oct 2017] |
| Gene Symbol |
RPE65 |
| Location |
1p31.3 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 68894506-68915642 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-RPE65-17539-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-RPE65-17539-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-RPE65-17539-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-RPE65-17539-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-RPE65-17539-AQ |
467nm |
418nm |
|
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