Gene-specific Copy Number Variation Probe-RGS14
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Catalog: |
CNVFP-RGS14-17160 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RGS14). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
RGS14 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RGS14 genes. This product achieves the purpose of detection by hybridizing with the RGS14 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Regulator Of G Protein Signaling 14 |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
Gene Symbol |
RGS14 |
Location |
5q35.3 |
Chromosome |
Chromosome5 |
Coordinates |
This gene maps to 176784843-176799599 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-RGS14-17160-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-RGS14-17160-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-RGS14-17160-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-RGS14-17160-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-RGS14-17160-AQ |
467nm |
418nm |
|
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