Gene-specific Copy Number Variation Probe-RASGRP4
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Catalog: |
CNVFP-RASGRP4-16955 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RASGRP4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
RASGRP4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RASGRP4 genes. This product achieves the purpose of detection by hybridizing with the RASGRP4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
RAS Guanyl Releasing Protein 4 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] |
Gene Symbol |
RASGRP4 |
Location |
19q13.2 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 38899697-38916945 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-RASGRP4-16955-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-RASGRP4-16955-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-RASGRP4-16955-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-RASGRP4-16955-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-RASGRP4-16955-AQ |
467nm |
418nm |
|
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