Gene-specific Copy Number Variation Probe-RAD17
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| Catalog: |
CNVFP-RAD17-16804 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (RAD17). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
RAD17 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to RAD17 genes. This product achieves the purpose of detection by hybridizing with the RAD17 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
RAD17 Checkpoint Clamp Loader Component |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013] |
| Gene Symbol |
RAD17 |
| Location |
5q13.2 |
| Chromosome |
Chromosome5 |
| Coordinates |
This gene maps to 68665123-68710630 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-RAD17-16804-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-RAD17-16804-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-RAD17-16804-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-RAD17-16804-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-RAD17-16804-AQ |
467nm |
418nm |
|
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