Gene-specific Copy Number Variation Probe-PTTG1
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| Catalog: |
CNVFP-PTTG1-16627 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PTTG1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PTTG1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PTTG1 genes. This product achieves the purpose of detection by hybridizing with the PTTG1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Pituitary Tumor-transforming 1 |
| Gene Summary [Provided by RefSeq] |
The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] |
| Gene Symbol |
PTTG1 |
| Location |
5q33.3 |
| Chromosome |
Chromosome5 |
| Coordinates |
This gene maps to 159848864-159855746 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PTTG1-16627-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PTTG1-16627-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PTTG1-16627-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PTTG1-16627-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PTTG1-16627-AQ |
467nm |
418nm |
|
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