Gene-specific Copy Number Variation Probe-PTPN12
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| Catalog: |
CNVFP-PTPN12-16625 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PTPN12). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PTPN12 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PTPN12 genes. This product achieves the purpose of detection by hybridizing with the PTPN12 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Tyrosine Phosphatase, Non-receptor Type 12 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| Gene Symbol |
PTPN12 |
| Location |
7q11.23 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 77166772-77269388 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PTPN12-16625-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PTPN12-16625-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PTPN12-16625-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PTPN12-16625-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PTPN12-16625-AQ |
467nm |
418nm |
|
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