Gene-specific Copy Number Variation Probe-PTPN1
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| Catalog: |
CNVFP-PTPN1-16685 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PTPN1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PTPN1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PTPN1 genes. This product achieves the purpose of detection by hybridizing with the PTPN1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Tyrosine Phosphatase, Non-receptor Type 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
| Gene Symbol |
PTPN1 |
| Location |
20q13.13 |
| Chromosome |
Chromosome20 |
| Coordinates |
This gene maps to 49126890-49201086 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PTPN1-16685-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PTPN1-16685-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PTPN1-16685-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PTPN1-16685-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PTPN1-16685-AQ |
467nm |
418nm |
|
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