Gene-specific Copy Number Variation Probe-PSEN2
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Catalog: |
CNVFP-PSEN2-16467 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PSEN2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PSEN2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PSEN2 genes. This product achieves the purpose of detection by hybridizing with the PSEN2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Presenilin 2 |
Gene Summary [Provided by RefSeq] |
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008] |
Gene Symbol |
PSEN2 |
Location |
1q42.13 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 227058272-227083804 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PSEN2-16467-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PSEN2-16467-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PSEN2-16467-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PSEN2-16467-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PSEN2-16467-AQ |
467nm |
418nm |
|
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