Gene-specific Copy Number Variation Probe-PRUNE2
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| Catalog: |
CNVFP-PRUNE2-16518 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PRUNE2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PRUNE2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PRUNE2 genes. This product achieves the purpose of detection by hybridizing with the PRUNE2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Prune Homolog 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
| Gene Symbol |
PRUNE2 |
| Location |
9q21.2 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 79226291-79521003 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PRUNE2-16518-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PRUNE2-16518-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PRUNE2-16518-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PRUNE2-16518-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PRUNE2-16518-AQ |
467nm |
418nm |
|
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