Gene-specific Copy Number Variation Probe-PRKAR2B
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| Catalog: |
CNVFP-PRKAR2B-16290 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PRKAR2B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PRKAR2B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PRKAR2B genes. This product achieves the purpose of detection by hybridizing with the PRKAR2B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Kinase CAMP-dependent Type II Regulatory Subunit Beta |
| Gene Summary [Provided by RefSeq] |
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
PRKAR2B |
| Location |
7q22.3 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 106685177-106802256 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PRKAR2B-16290-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PRKAR2B-16290-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PRKAR2B-16290-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PRKAR2B-16290-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PRKAR2B-16290-AQ |
467nm |
418nm |
|
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