Gene-specific Copy Number Variation Probe-PRKACA
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| Catalog: |
CNVFP-PRKACA-16300 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PRKACA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PRKACA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PRKACA genes. This product achieves the purpose of detection by hybridizing with the PRKACA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Kinase CAMP-activated Catalytic Subunit Alpha |
| Gene Summary [Provided by RefSeq] |
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015] |
| Gene Symbol |
PRKACA |
| Location |
19p13.12 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 14202506-14228559 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PRKACA-16300-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PRKACA-16300-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PRKACA-16300-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PRKACA-16300-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PRKACA-16300-AQ |
467nm |
418nm |
|
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