Gene-specific Copy Number Variation Probe-PRKAB1
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Catalog: |
CNVFP-PRKAB1-16302 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PRKAB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PRKAB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PRKAB1 genes. This product achieves the purpose of detection by hybridizing with the PRKAB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Protein Kinase AMP-activated Non-catalytic Subunit Beta 1 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008] |
Gene Symbol |
PRKAB1 |
Location |
12q24.23 |
Chromosome |
Chromosome12 |
Coordinates |
This gene maps to 120105760-120119429 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PRKAB1-16302-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PRKAB1-16302-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PRKAB1-16302-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PRKAB1-16302-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PRKAB1-16302-AQ |
467nm |
418nm |
|
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