Gene-specific Copy Number Variation Probe-PRDM16
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Catalog: |
CNVFP-PRDM16-16379 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PRDM16). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PRDM16 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PRDM16 genes. This product achieves the purpose of detection by hybridizing with the PRDM16 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
PR/SET Domain 16 |
Gene Summary [Provided by RefSeq] |
The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Gene Symbol |
PRDM16 |
Location |
1p36.32 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 2985741-3355185 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-PRDM16-16379-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PRDM16-16379-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PRDM16-16379-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PRDM16-16379-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PRDM16-16379-AQ |
467nm |
418nm |
|
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